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Center for Regenerative Medicine and Skeletal Development

The Center for Regenerative Medicine and Skeletal Development is an interdisciplinary group of basic scientists engaged in advancing understanding of the biology of bone, cartilage and skin, and exploring the potential for regeneration of these tissues lost in humans in response to trauma, disease and aging. The center was formed with an NIH infrastructure award to the UConn School of Dental Medicine, in alignment with the university’s strategic plan to build on existing extraordinary strengths in the area of musculoskeletal biology. Areas of research within the center encompass biomaterials; bone, cartilage and skin differentiation; craniofacial and tooth development; limb development and regeneration; and the use of stem cells for skeletal tissue regeneration and repair.

The center offers research education and training opportunities for postdoctoral fellows, graduate students, and Ph.D./D.M.D./M.D. degree students, in part through an NIH/NIDCR funded training grant. It is also the administrative home of the skeletal, craniofacial and oral biology graduate area of concentration.

In addition to directing independent research programs, integrated research efforts among Center faculty have led major endeavors including State of Connecticut stem cell group and limb development program projects. The center is committed to multidisciplinary research collaborations within and outside the University of Connecticut Health Center and is particularly aligned with the New England Musculoskeletal Institute and the Health Center's Stem Cell Institute.

The center consists of approximately 60 individuals including the director, faculty, fellows, graduate students and staff, and generates extramural funding currently exceeding $7 million. The 13 independent investigator laboratories of the center occupy adjacent space on two research floors, and include dedicated space for fluorescent microscopic imaging, cryohistology, radioactivity, and characterization and evaluation of biomaterials.

  
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